|Application ||IHC-F, IRMA|
|Other Accession||P05305, P14138|
|Calculated MW||19960 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Synthetic peptide corresponding to the c-terminal region of human endothelin (C,H,L,D,I,I,W), conjugated to BSA.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Endothelin-2, ET-2, Preproendothelin-2, PPET2, EDN2|
|Target/Specificity||Reacts with the C terminal of endothelins 1, 2 and 3. 3G10 does not react with the endothelin precursor molecule, big endothelin. The endothelins are potent vasoconstrictors and critical components in the progression of pulmonary arterial hypertension a devastating and rapidly progressive condition that leads to right ventricular strain and dysfunction.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Endothelin Antibody, clone 3G10 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
1. Yao, J. et al. (2001) Endothelin is a potent inhibitor of matrix metalloproteinase-2 secretion andactivation in rat mesangial cells.Am J Physiol Renal Physiol. 280: F628-635.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.