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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human Endothelin Antibody, clone 3G10    

Anti-Human Endothelin Antibody, clone 3G10

Rat Anti-Human Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-F, IRMA
Primary Accession P20800
Other Accession P05305, P14138
Reactivity Human
Host Rat
Clonality Monoclonal
Isotype IgG2b
Clone Names 3G10
Calculated MW 19960 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Synthetic peptide corresponding to the c-terminal region of human endothelin (C,H,L,D,I,I,W), conjugated to BSA.
Shelf Life 18 months from date of despatch.
Gene ID 1907
Other Names Endothelin-2, ET-2, Preproendothelin-2, PPET2, EDN2
Target/Specificity Reacts with the C terminal of endothelins 1, 2 and 3. 3G10 does not react with the endothelin precursor molecule, big endothelin. The endothelins are potent vasoconstrictors and critical components in the progression of pulmonary arterial hypertension a devastating and rapidly progressive condition that leads to right ventricular strain and dysfunction.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Endothelin Antibody, clone 3G10 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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References

1. Yao, J. et al. (2001) Endothelin is a potent inhibitor of matrix metalloproteinase-2 secretion andactivation in rat mesangial cells.
Am J Physiol Renal Physiol. 280: F628-635.

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Cat# ABD10471
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