|Calculated MW||30787 Da|
|Immunogen||Leu5-enkaphalin cinjugated to bovine serum albumin..|
|Shelf Life||18 months from date of despatch.|
|Other Names||Proenkephalin-A, Synenkephalin, Met-enkephalin, Opioid growth factor, OGF, PENK(114-133), PENK(143-183), Met-enkephalin-Arg-Gly-Leu, Leu-enkephalin, PENK(237-258), Met-enkephalin-Arg-Phe, PENK|
|Target/Specificity||Mouse anti-Human Leu5-enkephalin antibody, clone NOC.1 recognizes both Met5- and Leu5-enkephalin, secreted peptides which mimic the effect of opiate drugs. Mouse anti-Human Leu5-enkephalin antibody, clone NOC.1 recognizes well established enkephalin immunoreactive sites, but does not bind to areas known to contain beta-endorphin or dynorphin in IHC.Cross reactivity with Met5-enkephalin and lack of reactivity with the peptide Gly-Gly-Phe-Leu and other related peptides by inhibition of radiolabelled Leu5-enkephalin binding is noted (Anderssonet al.1995).|
|Preservative & Stabilisers||0.05% Thiomersal|
|Storage||Store at -20℃ only.|
|Precautions||Anti-Leu-Enkephalin Antibody, clone NOC.1 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Cuello, A. C. et al. (1984) Characterization and immunocytochemical application of monoclonal antibodies against enkephalinsJ Histochem Cytochem 32: 947 -957 2. Kaleczyc, J. et al. (2002) Distribution, immunohistochemical characteristics and nerve pathways of primary sensory neurons supplying the porcine vas deferens.Cell Tissue Res. 310: 9-17. 3. Bulc, M. et al. (2014) Immunohistochemical distribution of cocaine and amphetamine regulatory peptide-like immunoreactive (CART-LI) nerve fibers in the circular muscle layer and their relationship to other peptides in the human caecum.Acta Histochem. 116: 1029-36. 4. Gańko, M. & Calka, J. (2014) Localization and chemical coding of the dorsal motor vagal nucleus (DMX) neurons projecting to the porcine stomach prepyloric area in the physiological state and after stomach partial resection.J Mol Neurosci. 52 (1): 90-100. 5. Sienkiewicz, W. et al. (2010) Immunohistochemical characterization of neurones in the hypoglossal nucleus of the pig.Anat Histol Embryol. 39 (2): 152-9.
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