|Application ||WB, IHC-F|
|Calculated MW||32819 Da|
|Immunogen||Synthetic peptide with the amino acid sequence HDLSEALKEATKEVHC corresponding to residues 12-25 (+C-NH2 of human heme oxygenase 1.|
|Shelf Life||6 months from date of despatch.|
|Other Names||Heme oxygenase 1, HO-1, 22.214.171.124, HMOX1, HO, HO1|
|Target/Specificity||Rabbit anti-Human heme oxygenase 1 antibody recognizes human heme oxygenase-1 (HO-1), a 288 amino acid ezyme with a crucial role in heme catabolism, cleaving the heme ring to form biliverdin which is furhter processed to form bilirubin by a reductase enzyme. HO-1 acitivity is highest in the spleen where it is involved in the processing of senecent erythrocytes (Delabyet al.2012). HO-1expression can be increased during cellular stress, including heat shock (Ewinget al.1992). Baseline levels of expression are high in certain tissues, including spleen and liver. Enriched enzyme preparations are recommended for experimental analysis.|
|Preservative & Stabilisers||0.065% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Heme Oxygenase 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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