|Application ||WB, IHC-F, IP|
|Calculated MW||165469 Da|
|Purification||Purified IgG prepared by affinity chromatography|
|Immunogen||C-terminal fusion protein of rat NMDAR2A corresponding to amino acids 1253-1391.|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Glutamate receptor ionotropic, NMDA 2A, GluN2A, Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, Grin2a|
|Target/Specificity||Rabbit anti-Rat NMDA Receptor NR2A antibody recognizes the NMDA (N-methyl-D-aspartate) receptor NMDAR2A subunit.NMDA receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long term potentiation, an activity dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D).|
|Preservative & Stabilisers||Preservative Free|
|Storage||Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.|
|Precautions||Anti-Rat NMDA Receptor NR2A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Maliszewska-Cyna, E. et al. (2010) Diminished prevalence but preserved synaptic distribution of N-methyl-D-aspartate receptor subunits in the methyl CpG binding protein 2(MeCP2)-null mouse brain.Neuroscience. 168: 624-32 2. Asaka, Y. et al. (2006) Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome.Neurobiol Dis. 21: 217-27.
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