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Anti-Rat NMDA Receptor NR2B Antibody

Rabbit Anti-Rat Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q00960
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 166071 Da
Additional Information
Other Species M,H,Fish
Purification Purified IgG prepared by affinity chromatography
Immunogen C-terminal fusion protein of Rat NMDAR2B (30kDa) corresponding to amino acids 984-1104.
Shelf Life 12 months from date of reconstitution.
Gene ID 24410
Other Names Glutamate receptor ionotropic, NMDA 2B, GluN2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, NMDAR2B, NR2B, Grin2b
Target/Specificity Rabbit anti-Rat NMDA Receptor NR2B antibody recognises the 180kDa NMDA (N-methyl-D-aspartate) receptor NMDAR2B subunit.NMDA receptors are a class of ionotropic glutamate receptors. NMDA channels have been shown to be involved in long term potentiation, an activity dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), or NMDAR2D (GRIN2D).
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Rat NMDA Receptor NR2B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Maliszewska-Cyna, E. et al. (2010) Diminished prevalence but preserved synaptic distribution of N-methyl-D-aspartate receptor subunits in the methyl CpG binding protein 2(MeCP2)-null mouse brain.
Neuroscience. 168: 624-32 2. Asaka, Y. et al. (2006) Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome.
Neurobiol Dis. 21: 217-27. 3. Grosshans, D.R. and Browning, M.D. (2001) Protein kinase C activation induces tyrosine phosphorylation of the NR2A and NR2B subunits of the NMDA receptor.
J Neurochem. 76: 737-44.

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Cat# ABD10667
(40 western blots)
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