|Calculated MW||10963 Da|
|Shelf Life||18 months from date of despatch.|
|Other Names||Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein, BGLAP|
|Target/Specificity||ABD10683 is specific for intact osteocalcin and recognizes an epitope towards the C-terminal of the molecule.Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kDa), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Paget’s disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Osteocalcin Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Bielby RC et al.(2004)In vitro differentiation and in vivo mineralization of osteogenic cells derived from human embryonic stem cells.Tissue Eng. 10 (9-10): 1518-25. 2. Lopes, M.A. et al. (1998) Flow cytometry for assessing biocompatibility.J Biomed Mater Res. 41 (4): 649-56. 3. Kaivosoja, E. et al. (2015) The effect of pulsed electromagnetic fields and dehydroepiandrosterone on viability and osteo-induction of human mesenchymal stem cells.J Tissue Eng Regen Med. 9 (1): 31-40.
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