Anti-Human Parathyroid Hormone Related Peptide Antibody, clone BGN/09/5215
Mouse Anti-Human Monoclonal Antibody
|Calculated MW||20194 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Immunogen||Synthetic peptide corresponding to the amino acids 93-107 of human PTHrP conjugated to Keyhole limpet Haemocyanin (KLH).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Parathyroid hormone-related protein, PTH-rP, PTHrP, Parathyroid hormone-like protein, PLP, PTHrP[1-36], PTHrP[38-94], Osteostatin, PTHrP[107-139], PTHLH, PTHRP|
|Target/Specificity||Mouse anti-Human parathyroid hormone related protein antibody, clone BGN/09/5215 is specific for human parathyroid hormone related protein (PTHrP). PTHrP is a critical regulator of cell and organ growth, development and survival (Wysolmerski 2012).PTHrP shares the same N-terminal as Parathyroid hormone (PTH) which allows it to bind to Parathyroid Hormone Receptor 1 (Pioszaket al.2009). PTHrP plays an important role acting both as a circulating and local factor in the development of humoral hypercalcemia of malignancy and local osteolysis associated with metastatic cancer (Mundy and Edwards 2008)|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Parathyroid Hormone Related Peptide Antibody, clone BGN/09/5215 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Hildreth, B.E. 3rd. et al. (2010) PTHrP 1-141 and 1-86 increase in vitro bone formation.J Surg Res. 162: e9-17.
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