|Application ||IHC-P, IHC-F, E|
|Clone Names||3F6B3 (10H6)|
|Immunogen||This antibody was raised against insoluble peptidoglycan obtained by TCA-heat and ethanol extraction of Streptococcus mutans BHT cells.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti-Peptidoglycan antibody, clone 3F6B3 recognizes the 3D polymer complex structure of peptidoglycan (PG). In a competitive immunoassay format, several compounds were found to be ineffective as inhibitors; muramyldipeptide, N-acetylglucosamine, chitin and acid hydrolyzed chitin. The epitope appears to consist of discontinuous glycan and/or amino acid residues.|
|Preservative & Stabilisers||Preservative Free|
|Storage||Store at -20℃ only.|
|Precautions||Anti-Peptidoglycan Antibody, clone 3F6B3 (10H6) (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Miklossy, J. et al(2004)Borrelia burgdorferi persists in the brain in chronic lyme neuroborreliosis and may be associated with Alzheimer disease.J. Alzheimer's Dis. 6: 639-649. 2. Wu, L. et al. (2007) Bacterial peptidoglycan breaks down intestinal tolerance via mast cell activation: the role of TLR2 and NOD2.Immunol Cell Biol. 85: 538-45. 3. Rennemeier, C. et al. (2007) Thrombospondin-1 promotes cellular adherence of gram-positive pathogens via recognition of peptidoglycan.FASEB J. 21 (12): 3118-32. 4. Schweitzer, M.H. et al. (2016) Testing the Hypothesis of Biofilm as a Source for Soft Tissue and Cell-Like Structures Preserved in Dinosaur Bone.PLoS One. 11 (2): e0150238. 5. Miklossy J et al. (2008) Persisting atypical and cystic forms of Borrelia burgdorferi and local inflammation in Lyme neuroborreliosis.J Neuroinflammation. 5: 40.
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