Anti-Peptidoglycan Antibody, clone 3F6B3 (10H6) (Ascites)
Mouse Anti-Bacterial Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-P, IHC-F, E |
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Reactivity | Bacteria |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Clone Names | 3F6B3 (10H6) |
Immunogen | This antibody was raised against insoluble peptidoglycan obtained by TCA-heat and ethanol extraction of Streptococcus mutans BHT cells. |
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Shelf Life | 18 months from date of despatch. |
Target/Specificity | Mouse anti-Peptidoglycan antibody, clone 3F6B3 recognizes the 3D polymer complex structure of peptidoglycan (PG). In a competitive immunoassay format, several compounds were found to be ineffective as inhibitors; muramyldipeptide, N-acetylglucosamine, chitin and acid hydrolyzed chitin. The epitope appears to consist of discontinuous glycan and/or amino acid residues. |
Preservative & Stabilisers | Preservative Free |
Storage | Store at -20℃ only. |
Precautions | Anti-Peptidoglycan Antibody, clone 3F6B3 (10H6) (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures. |

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References
1. Miklossy, J. et al(2004)Borrelia burgdorferi persists in the brain in chronic lyme neuroborreliosis and may be associated with Alzheimer disease.J. Alzheimer's Dis. 6: 639-649. 2. Wu, L. et al. (2007) Bacterial peptidoglycan breaks down intestinal tolerance via mast cell activation: the role of TLR2 and NOD2.Immunol Cell Biol. 85: 538-45. 3. Rennemeier, C. et al. (2007) Thrombospondin-1 promotes cellular adherence of gram-positive pathogens via recognition of peptidoglycan.FASEB J. 21 (12): 3118-32. 4. Schweitzer, M.H. et al. (2016) Testing the Hypothesis of Biofilm as a Source for Soft Tissue and Cell-Like Structures Preserved in Dinosaur Bone.PLoS One. 11 (2): e0150238. 5. Miklossy J et al. (2008) Persisting atypical and cystic forms of Borrelia burgdorferi and local inflammation in Lyme neuroborreliosis.J Neuroinflammation. 5: 40.

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