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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Pyruvate Kinase Antibody    

Anti-Pyruvate Kinase Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P11974
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 58048 Da
Additional Information
Purification Ig fraction prepared by a multi-step process including delipidation, salt fractionation and ion exchange chromatography followed by dialysis.
Immunogen Pyruvate kinase from rabbit muscle.
Shelf Life 18 months from date of despatch.
Gene ID 100008676
Other Names Pyruvate kinase PKM, 2.7.1.40, Pyruvate kinase muscle isozyme, PKM, PKM2
Target/Specificity Pyruvate kinase is an enzyme invloved in glycolysis that catalyzes the transfer of phosphate from phosphoenol pyruvate (PEP) to ADP yielding ATP and pyruvate. Pyruvate can then be converted to Acetyl CoA and enter the TCA cycle. At least three molecular forms with pyruvate kinase activity are known. PK1, the red cell form, is deficient in a type of hemolytic anemia. PK2 is found in kidney. PK3 is found in leukocytes, muscle, platelets, and brain but not in red cells or kidney.Assay by IEP gives a single precipitin arc against anti-goat serum as well as partially purified rabbit muscle pyruvate kinase. This antibody has been reported to react with all forms of pyruvate kinase.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Pyruvate Kinase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD10733
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