Anti-Respiratory Syncytial Virus Antibody (Biotin)
Goat Anti-Viral Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-F, E, Func |
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Reactivity | Virus |
Host | Goat |
Clonality | Polyclonal |
Isotype | Polyclonal IgG |
Immunogen | Human RSV isolate. |
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Shelf Life | 18 months from the date of despatch. |
Target/Specificity | Goat anti-respiratory syncitial virus polyclonal antibody recognizes respiratory syncytial virus (RSV) a negative-sense, single-stranded RNA virus and member of the Paramyxoviridae family. RSV causes respiratory tract infections in patients of all ages, but particularly affects infants and the immunosuppressed.RSV encodes three envelope glycoproteins, a small hydrophobic (SH) protein of unknown function, a glycoprotein (G) known as the attachment protein, and a fusion (F) protein. The F protein directs fusion of viral and cellular membranes, resulting in viral penetration, and can lead to the formation of syncytia. The F protein is thought to be the principal antigen responsible for inducing an immune response.Goat anti-respiratory syncitial virus does not react with Parainfluenza 1-3, Influenza A and B, Adenovirus or uninfected HEp-2 or WI-38 cells. Goat anti-respiratory syncitial virus polyclonal antibody is neutralizing and reacts well with bovine isolates. |
Preservative & Stabilisers | 0.09% Sodium Azide (NaN3) |
Storage | Store at +4℃ or at -20 ℃. |
Precautions | Anti-Respiratory Syncytial Virus Antibody (Biotin) is for research use only and not for use in diagnostic or therapeutic procedures. |

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Provided below are standard protocols that you may find useful for product applications.
References
1. Culley, F.J. et al. (2006) Role of CCL5 (RANTES) in viral lung disease. J Virol. 80: 8151-7. 2. Numata, M. et al. (2010) Pulmonary surfactant phosphatidylglycerol inhibits respiratory syncytial virus-induced inflammation and infection.Proc Natl Acad Sci U S A. 107: 320-5. 3. Roux, X. et al. (2008) Sub-nucleocapsid nanoparticles: a nasal vaccine against respiratory syncytial virus.PLoS One. 3: e1766. 4. Olszewska, W. et al. (2011) Antiviral and lung protective activity of a novel RSV fusion inhibitor in a mouse model.Eur Respir J. 38: 401-8. 5. Fonceca AM et al. (2012) Primary airway epithelial cultures from children are highly permissive to respiratory syncytial virus infection.Thorax. 67 (1): 42-8. 6. Ryzhakov, G. et al. (2011) IL-17 Boosts Proinflammatory Outcome of Antiviral Response in Human Cells.J Immunol. 187: 5357-62. 7. Fricke J et al. (2013) p38 and OGT sequestration into viral inclusion bodies in cells infected with human respiratory syncytial virus suppresses MK2 activities and stress granule assembly.J Virol. 87 (3): 1333-47. 8. Kipper, S. et al. (2015) New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein.Mol Cell Proteomics. 14 (3): 532-43. 9. Russell, R.F. et al. (2015) Partial Attenuation of Respiratory Syncytial Virus with a Deletion of a Small Hydrophobic Gene Is Associated with Elevated Interleukin-1β Responses.J Virol. 89 (17): 8974-81. 10. Currie S. M. et al. (2016) Cathelicidins Have Direct Antiviral Activity against Respiratory Syncytial Virus In Vitro In Vivo in Mice and Humans.The Journal of Immunology. Feb 12 [Epub ahead of print]

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