|Application ||IHC-P, IHC-F|
|Calculated MW||12736 Da|
|Immunogen||Somatostatin conjugated to thyroglobulin.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Somatostatin, Growth hormone release-inhibiting factor, Somatostatin-28, Somatostatin-14, SST|
|Target/Specificity||Rat anti-Human Somatostatin antibody, clone YC7 is specific for somatostatin. A hormone involved in endocrine system regulation through interactions with pituitary growth hormone, thyroid stimulating hormone, and a number of hormones of the gastrointestinal tract. Somatostatin has active 14 amino acid and 28 amino acid forms, produced by alternate cleavage of the gene product.This antibody does not cross react with enkephalins, other endorphins, substance P, or CGRP. It partially cross reacts with somatostatin fragments. The epitope recognised by this antibody lies within the 1-14 amino acid sequence of cyclic somatostatin.|
|Preservative & Stabilisers||0.05% Thiomersal|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Somatostatin Antibody, clone YC7 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Pidsudko, Z. et al. (2004) Distribution and chemical coding of neurons in intramural ganglia of the porcine urinary bladder trigone.Folia Histochem Cytobiol. 42: 3-11. 2. Van Nassauw, L. et al. (2002) Neurochemical identification of enteric neurons expressing P2X(3) receptors in the guinea-pig ileum.Histochem Cell Biol. 118 (3): 193-203. 3. Geuens, E. et al. (2003) A globin in the nucleus! J Biol Chem. 278: 30417-20. 4. Kaleczyc, J. et al. (2002) Distribution, immunohistochemical characteristics and nerve pathways of primary sensory neurons supplying the porcine vas deferens.Cell Tissue Res. 310: 9-17. 6. Pidsudko, Z. (2014) Immunohistochemical characteristics and distribution of sensory dorsal root Ganglia neurons supplying the urinary bladder in the male pig.J Mol Neurosci. 52 (1): 71-81. 7. Hens, J. et al. (2001) Morphological and neurochemical identification of enteric neurones with mucosal projections in the human small intestine.J Neurochem. 76: 464-71. 8. Hens, J. et al. (2000) Mucosal projections of enteric neurons in the porcine small intestine.J Comp Neurol. 421: 429-36. 9. Rychlik, A. et al. (2002) Diarrhea-Induced Changes in Chemical Phenotypes of Enteric Structures in the Pig are not Sufficient to Discriminate between the Viral and Bacterial Etiology of the Disease.Bull. Vet. Inst. Pulawy 46, 187-196. 5. Milstein, C. & Cuello, A.C. (1983) Hybrid hybridomas and their use in immunohistochemistry.Nature. 305: 537-40.
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