Anti-Chicken Spectrin (Non-Erythroid) Antibody, clone AA6 (7A3)
Mouse Anti-Chicken Monoclonal Antibody
|Application ||WB, IF, IP, CHIP|
|Clone Names||AA6 (7A3)|
|Calculated MW||285363 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Immunogen||Chicken blood cell membrane purified by hypotonic lysis and mechanical enucleation.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Spectrin alpha chain, non-erythrocytic 1, Alpha-II spectrin, Fodrin alpha chain, SPTAN1, SPTA2|
|Target/Specificity||Mouse anti-Chicken spectrin, clone AA6, recognizes spectrin alpha chain, non-erythrocytic 1, also known as Alpha-II spectrin and Fodrin alpha chain, encoded by the SPTAN1 gene. Mouse anti-chicken spectrin recognizes both chicken spectrin and the alpha chain of non-erythroid spectrin in mammalian cells.Clone AA6 reacts with the 240 kDa full length spectrin alpha, the ~150 kDa, 145kDa characteristic breakdown products of calpain and caspase-3 (Nathet al.1996) and the ~120kDaproduct, a result of caspase-3 activation (Nathet al.1998).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Chicken Spectrin (Non-Erythroid) Antibody, clone AA6 (7A3) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Ylikoski, J. et al. (1992) Distribution of F-actin and fodrin in the hair cells of the guinea pig cochlea as revealed by confocal fluorescence microscopyHear Res 60: 80 - 88 1. Ylikoski, J. et al. (1990) Nonerythroid spectrin (fodrin) is a prominent component of the cochlear hair cellsHear Res 43: 199 - 203
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