|Clone Names||5E6 (BGN/6D7)|
|Calculated MW||304790 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G.|
|Immunogen||Purified human thyroglobulin.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Thyroglobulin, Tg, TG|
|Target/Specificity||Mouse anti-Human Thyroglobulin antibody, clone 5E6 recognises human thyroglobulin (Tg), a 2768 amino acid ~670kDa homodimeric protein containing multiple thyroglobulin type 1 domains. Thyroglobulin is produced by the thyroid gland and is a precursor in the production of the thyroid hormones Triiodothyronine (T3) and Thyroxine (T4), important for regulating metabolic processes in the body (Uniprot: P01266).Mutations in the thyroglobulin gene can lead to developmental and autoimmune diseases including Thyroid dyshormonogenesis 3 (Targovniket al.2010) and Autoimmune thyroid disease 3 (Banet al.2003).Mouse anti-Human Thyroglobulin antibody, clone 5E6 has been used successfully as a detection reagent in a sensitive sandwich ELISA for the detection of thyroglobulin in human serum and plasma samples.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Thyroglobulin Antibody, clone 5E6 (BGN/6D7) is for research use only and not for use in diagnostic or therapeutic procedures.|
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