|Application ||WB, IHC-F, IF, FC|
|Calculated MW||33068 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G.|
|Immunogen||Denatured Tissue factor isolated from human brain by the Factor VII affinity method (Guhaet al.1986).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Tissue factor, TF, Coagulation factor III, Thromboplastin, CD142, F3|
|Target/Specificity||Mouse anti-Human CD142 antibody, clone TF9-10H10 recognizes human CD142, also known as Tissue Factor, is the membrane receptor for coagulation factors VII and VIIa and is the cell surface initiator of coagulation. It is the major molecule of this type and is criticial for controlling hemostasis, thrombosis and inflammation.Mouse anti-Human CD142 antibody, clone TF9-10H10 recognizes an epitope within the extracellular domain, epitope locus I. It recognizes both the reduced and native non-reduced human and primate tissue factors. It does not inhibit coagulation or neutralize factor VII binding to CD142.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD142 Antibody, clone TF9-10H10 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Morrissey, J. H. et al. (1988) Monoclonal antibody analysis of purified and cell-associated tissue factor. Thromb. Res. 52: 247-261. 1. Contrino, J. et al. (1994) In situ characterization of antigenic and functional tissue factor expression in human tumors utilizing monoclonal antibodies and recombinant factor VIIa as probes.Am. J. Path. 145: 1315-1322. 3. Drake, T. A. et al. (1989) Selective cellular expression of tissue factor in human tissues. Implications fordisorders of hemostasis and thrombosis.Am. J. Pathol. 134: 1087-1097. 4. Stearns-Kurosawa, D. J. et al. (2006) Sepsis and pathophysiology of anthrax in a nonhuman primate model.Am. J. Pathol. 169: 433-444. 5. Mueller, B. M. et al. (1992) Expression of tissue factor by melanoma cells promotes efficient hematogenousmetastasis.Proc. Natl. Acad. Sci. U. S. A. 89: 11832-11836. 6. Agmon-Levin, N. et al. (2011) Vitamin D: an instrumental factor in the anti-phospholipid syndrome by inhibition of tissue factor expression.Ann Rheum Dis. 70: 145-50. 7. Ruf, W. et al. (1991) Rehemtulla A, Edgington TS. Antibody mapping of tissue factor implicates two different exon-encoded regions in function.Biochem. J. 278: 729-33.
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