|Calculated MW||17006 Da|
|Purification||Purified Ig prepared by ion exchange chromatography|
|Immunogen||Mature human recombinant TGF-alpha conjugated to KLH.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Protransforming growth factor alpha, Transforming growth factor alpha, TGF-alpha, EGF-like TGF, ETGF, TGF type 1, TGFA|
|Target/Specificity||ABD10807 recognises TGF-alpha (transforming growth factor alpha) from human, rat and bovine tissues and fluids. TGF-alpha is a 50 amino acid EGF-related polypeptide expressed in a range of tissues, including skin, pancreas, liver, duodenum, salivary glands, urinary and respiratory systems, and the developing and mature central nervous system (CNS).TGF-alpha is produced by monocytes, keratinocytes and neuronal cells and stimulates the proliferation of a range of epidermal and epithelial cells, through binding to the epidermal growth factor receptor (EGFR). TGF-alpha is mitogenic for multipotent neural progenitors and is involved in astrogliosis.This antibody does not react with EGF or TGF-beta.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human TGF alpha Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Ju, W. et al. (1991) Tumorigenic transformation of NIH 3T3 cells by the autocrine synthesis of transforming growth factor alpha. New Biol. 3: 380-388.
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