|Application ||WB, IHC-P, IHC-F|
|Clone Names||Ubi-1 (242.9)|
|Immunogen||Purified ubiquitin (Bovine RBC) conjugated to Keyhole Limpet Haemocyanin.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti-bovine ubiquitin antibody, clone Ubi-1 is specific for ubiquitin an 8.5 kDa, 76 amino acid protein, highly conserved in eukaryotes. Clone Ubi-1 shows staining of tangle material in Alzheimer affected brain, and also stains other pathological inclusions such as Lewy bodies (in Parkinson's disease) and Pick bodies (in Pick's disease).|
|Preservative & Stabilisers||0.06% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Bovine Ubiquitin Antibody, clone Ubi-1 (242.9) (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Meyer, E. M. et al. (1986) Antibodies directed against ubiquitin inhibit high affinity [3H]choline uptake in rat cerebral cortical synaptosomes.J. Biol. Chem. 261: 14365-14368. 1. Shaw, G. et al. (1988) Ubiquitin and Microtubule-Associated Protein Tau Immunoreactivity Each Define Distinct Structures with Differing Distributions and Solubility Properties in Alzheimer Brain. PNAS USA 85: 2854-2858. 1. Perry, G. et al. (1987) Ubiquitin is detected in neurofibrillary tangles and senile plaqueneurites of Alzheimer disease brains.PNAS USA 84: 3033-3036.
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