|Application ||WB, IHC-F, E|
|Clone Names||8E6 (1.110)|
|Calculated MW||54306 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Purified vitronectin from human plasma|
|Shelf Life||18 months from date of despatch.|
|Other Names||Vitronectin, VN, S-protein, Serum-spreading factor, V75, Vitronectin V65 subunit, Vitronectin V10 subunit, Somatomedin-B, VTN|
|Target/Specificity||ABD10831 is specific for vitronectin and will react with the native and denatured forms. It does not cross react with fibronectin.Vitronectin is one of the 2 most important cell adhesive proteins found in the blood and extracellular matrix. It exists as a mixture of 2 monomeric glycoproteins that mediate cell adhesion through an interaction between the R-G-D sequence, present in the cell binding domains, and several different integrin receptors. It is also known as a complement lysis inhibitor and as a scavenger protein for macromolecular products of the complement and homeostasis cascades.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Vitronectin Antibody, clone 8E6 (1.110) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Hayman, E. G. et al. (1983) Serum spreading factor (vitronectin) is present at the cell surface and in tissues.Proc. Natl. Acad. Sci. U. S. A. 80(13): 4003-4007.
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