|Application ||WB, E|
|Calculated MW||35003 Da|
|Purification||Antisera to mouse CD254 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||Recombinant mouse CD254.|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, RANKL, TNF-related activation-induced cytokine, TRANCE, CD254, Tumor necrosis factor ligand superfamily member 11, membrane form, Tumor necrosis factor ligand superfamily member 11, soluble form, Tnfsf11, Opgl, Rankl, Trance|
|Target/Specificity||Rabbit anti-Mouse CD254 antibody recognizes mouse CD254, otherwise known as sRANKL, a 19.4kDa soluble protein and member of the TNF superfamily, comprising the full-length of the TNF-like extracellular domain of RANKL, expressed abundantly by T lymphocytes and cells of osteoblastic origin.CD254 plays a role in the differentiation/maturation of osteoclast precursors and may act as a regulator of T lymphocytes and dendritic cell interactions, as demonstrated by its ability to augment the dendritic cell stimulation of naïve T-cell proliferation, in a mixed lymphocyte reaction (MLR).|
|Preservative & Stabilisers||Preservative Free|
|Storage||Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.|
|Precautions||Anti-Mouse CD254 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Anderson, D.M. et al. (1997) A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.Nature. 390: 175-179.
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