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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Mouse CD254 Antibody    

Anti-Mouse CD254 Antibody

Rabbit Anti-Mouse Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O35235
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 35003 Da
Additional Information
Purification Antisera to mouse CD254 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Recombinant mouse CD254.
Shelf Life 12 months from date of reconstitution.
Gene ID 21943
Other Names Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, RANKL, TNF-related activation-induced cytokine, TRANCE, CD254, Tumor necrosis factor ligand superfamily member 11, membrane form, Tumor necrosis factor ligand superfamily member 11, soluble form, Tnfsf11, Opgl, Rankl, Trance
Target/Specificity Rabbit anti-Mouse CD254 antibody recognizes mouse CD254, otherwise known as sRANKL, a 19.4kDa soluble protein and member of the TNF superfamily, comprising the full-length of the TNF-like extracellular domain of RANKL, expressed abundantly by T lymphocytes and cells of osteoblastic origin.CD254 plays a role in the differentiation/maturation of osteoclast precursors and may act as a regulator of T lymphocytes and dendritic cell interactions, as demonstrated by its ability to augment the dendritic cell stimulation of naïve T-cell proliferation, in a mixed lymphocyte reaction (MLR).
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Mouse CD254 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Anderson, D.M. et al. (1997) A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.
Nature. 390: 175-179.

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Cat# ABD10846
(40 western blots)
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