|Application ||WB, E|
|Calculated MW||11017 Da|
|Purification||Antiserum to mouse MCP-2 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Recombinant mouse MCP-2|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||C-C motif chemokine 8, Monocyte chemoattractant protein 2, Monocyte chemotactic protein 2, MCP-2, Small-inducible cytokine A8, Ccl8, Mcp2, Scya8|
|Target/Specificity||Rabbit anti-Mouse MCP-2 antibody recognizes mouse MCP-2 (Monocyte Chemoattractant Protein 2), otherwise known as CCL8, a CC chemokine originally isolated from the human osteosarcoma cell line MG-63, which is expressed at highest levels in peripheral blood cells and the small intestine.MCP-2 acts as a chemoattractant for monocytes, lymphocytes, eosinophils and basophils, and signals through binding to the common MCP receptor, chemokine (C-C motif) receptor 2 (CCR2), and also CCR1 and CCR3. Proteolytic cleavage of MCP-2 into the NH2-terminally truncated form, MCP-2 (6-76), results in the loss of chemotactic activity, forming a functional CC chemokine inhibitor, which may be important during inflammatory responses.|
|Preservative & Stabilisers||Preservative Free|
|Storage||Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.|
|Precautions||Anti-Mouse MCP-2 Antibody (Biotin) is for research use only and not for use in diagnostic or therapeutic procedures.|
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