|Application ||WB, IHC-P, E|
|Calculated MW||40045 Da|
|Purification||Antiserum to mouse CDw198 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic peptide PNVTMTDYYPDFFTAPCDAEFLLRGSM corresponding to amino acids 7-33 of mouse CDw198.|
|Shelf Life||18 months from date of despatch.|
|Other Names||C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, CDw198, Ccr8, Cmkbr8, Ter1|
|Target/Specificity||Goat anti-mouse CDw198 polyclonal antibody specifically recognizes mouse CDw198, otherwise known as CCR8 (C-C chemokine receptor type 8), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts a high-affinity receptor for the chemokine I-309 (CCL1), implicated in the regulation of monocyte chemotaxis and thymocyte apoptosis.CDw198 is constitutively expressed by monocytes, preferentially expressed on Th2 (type 2 helper T) cells, and acts as a co-receptor with CD4 for HIV1 infection.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at -20℃ only.|
|Precautions||Anti-Mouse CDw198 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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