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Anti-Mouse CD193 (N-Terminal) Antibody

Goat Anti-Mouse Polyclonal Antibody

  • IHC - Anti-Mouse CD193 (N-Terminal) Antibody  ABD10854
    Staining of paraffin embedded mouse spleen with Goat anti Mouse CD193
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51678
Reactivity Mouse
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 41783 Da
Additional Information
Purification Antiserum to mouse CD193 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Synthetic peptide TDEIKTVVESFETTPYEYEWAPPC corresponding to amino acids 5-28 within the N-terminal region of mouse CD193.
Shelf Life 18 months from date of despatch.
Gene ID 12771
Other Names Probable C-C chemokine receptor type 3, C-C CKR-3, CC-CKR-3, CCR-3, CCR3, CKR3, Macrophage inflammatory protein 1-alpha receptor-like 2, MIP-1 alpha RL2, CD193, Ccr3, Cmkbr1l2, Cmkbr3
Target/Specificity Goat anti-Mouse CD193 antibody recognizes an epitope within the N-terminal (NT) region of mouse CD193, otherwise known as C-C chemokine receptor type 3 or CCR3. CD193 is a 359 amino acid ~42 kDa multi pass transmembrane glycoprotein and member of the G-protein coupled receptor 1 family (UniProt: P51678). CD193 is expressed by basophils, eosinophils, microglia, Th2 cells and dendritic cells. CD193 acts as a receptor for eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13) and RANTES (CCL5), the former being a chemoattractant for eosinophils and basophils. CD193 is involved in leukocyte chemotaxis and, along with CD191 (CCR1), is implicated as a regulator of T cell and dendritic cell interaction during the process of antigen presentation. CD193 is implicated as an activator of eosinophils in allergic lung disease, and is a useful TH2 cell marker in monitoring immune responses. Goat anti-Mouse CD193 antibody is reported as suitable for use in immunocytochemistry on acetone fixed cells.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3); 0.1% Bovine Serum Albumin;
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse CD193 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD10854
(40 western blots)
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