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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Mouse CD289 (N-Terminal) Antibody    

Anti-Mouse CD289 (N-Terminal) Antibody

Goat Anti-Mouse Polyclonal Antibody

  • IHC - Anti-Mouse CD289 (N-Terminal) Antibody  ABD10855
    Staining of paraffin embedded mouse thymus with Goat anti mouse CD289
  • IHC-P - Anti-Mouse CD289 (N-Terminal) Antibody  ABD10855
    Staining of paraffin embedded human spleen with Goat anti mouse CD289
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NR96
Other Accession Q9EQU3
Reactivity Mouse
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 115860 Da
Additional Information
Other Species H
Purification Antiserum to mouse CD289 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Synthetic peptide LSLKYNNLTKVPRQLPPSLEY-C corresponding to amino acids 204-224 within the N-terminal region of mouse CD289.
Shelf Life 18 months from date of despatch.
Gene ID 54106
Other Names Toll-like receptor 9, CD289, TLR9
Target/Specificity Goat anti-Mouse CD289 antibody recognises murine Toll-like receptor 9, also known as CD289 or TLR9. CD289 is an 1032 amino acid ~120 kDa endosomal single pass type I transmembrane glycoprotein with a number of leucine rich repeats and a single TIR domain (UniProt: Q9NR96). Goat anti-Mouse CD289 antibody recognizes an epitope within the N-terminal (NT) region of CD289, a member of the toll-like receptor family, which triggers MyD88 and TRAF6, resulting in NF-kappaB activation, cytokine secretion and the inflammatory response. CD289 acts as a receptor for unmethylated cytidine-phosphate-guanosine dinucleotides in bacterial DNA (CpG-DNA), playing a primary role in pathogen recognition and activation of innate immunity andhas been shown to play a role in defence against systemic mouse cytomegalovirus infection. Goat anti-Mouse CD289 antibody is reported as suitable for use in immunocytochemistry on acetone fixed cells.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3); 0.1% Bovine Serum Albumin;
Storage Store at -20℃ only.
PrecautionsAnti-Mouse CD289 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Ripoll, V.M. et al. (2010) Macrophages from BALB/c and CBA/Ca mice differ in their cellular responses to Streptococcus pneumoniae.
J Leukoc Biol. 87: 735-41.

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Cat# ABD10855
(40 western blots)
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