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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Rat Endothelin B Receptor (C-Terminal) Antibody    

Anti-Rat Endothelin B Receptor (C-Terminal) Antibody

Sheep Anti-Rat Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P48302
Other Accession P24530, P21451
Reactivity Rat
Host Sheep
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 49561 Da
Additional Information
Other Species M,H
Purification Antiserum to rat ET-B (CT) was raised by repeated immunisation of sheep with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Keyhole limpet haemocyanin (KLH) conjugated C-terminal peptide KANDHGYDNFRSSNN corresponding to amino acids 424 to 437 of rat endothelin B receptor.
Shelf Life 18 months from date of despatch.
Gene ID 13618
Other Names Endothelin B receptor, ET-B, ET-BR, Endothelin receptor non-selective type, Ednrb
Target/Specificity ABD10868 specifically recognises an epitope within the C-terminal (CT) region of endothelin B receptor (ET-B), a widely distributed transmembrane protein and member of the G-protein coupled receptor 1 family, which acts as a non-specific receptor for endothelin 1, 2, and 3, and mediates its action by G protein association and activation of a phosphatidylinositol-calcium second messenger system. ABD10868 recognizes epitopes on the cytoplasmic side of the receptor and therefore the cell membrane must be permeable to the antibody. ABD10868 does not block the binding of endothelins. ABD10868 is reported as suitable for use in immunocytochemistry on acetone fixed cells.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃. DO NOT FREEZE.
PrecautionsAnti-Rat Endothelin B Receptor (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD10868
(40 western blots)
Availability: Inquire
Bulk Size
Seasonal Special on Bulk Order
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