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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Human TLR5 Antibody    

Anti-Human TLR5 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • WB - Anti-Human TLR5 Antibody  ABD10878
    Western blot analysis of rat brain lysate probed with Rabbit anti Human TLR5 at 0.5(A), 1(B) and 2(C) ug/ml
  • IHC-P - Anti-Human TLR5 Antibody  ABD10878
    Formalin fixed, paraffin embedded rat brain stained with Rabbit anti Human TLR5 following heat mediated antigen retrieval using sodium citrate buffer (pH6.0)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60602
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 97834 Da
Additional Information
Other Species Rat,M
Purification Antisera to human TLR5 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Synthetic peptide corresponding to a 16 amino acid sequence located near the centre of human TLR5.
Shelf Life 18 months from date of despatch.
Gene ID 7100
Other Names Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3, TLR5, TIL3
Target/Specificity Rabbit anti-Human TLR5 antibody recognizes human Toll-like receptor 5 (TLR5), a 97.6kDa member of the evolutionarily conserved toll-like receptor family (TLRs), expressed at high levels in the liver and detectable in small amounts in most other tissues.TLRs play an important role in the recognition of invading microbial pathogens during innate immunity, acting through adaptor molecules such as MyD88 and TRAF6. TLR5 acts via a cytokine signaling pathway to induce the activation of NF-kappaB and in turn tumour necrosis factor alpha and has been shown to recognize flagellin from both Gram-positive and Gram-negative bacteria.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human TLR5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Hayashi, F. et al. (2001) The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5.
Nature. 410: 1099-1103.2. Hawn, T. R. et al. (2003) A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to Legionnaire’s disease.
J. Exp. Med. 198: 1563-1572.

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Cat# ABD10878
(40 western blots)
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