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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Caveolin 1 Antibody    

Anti-Caveolin 1 Antibody

Goat Anti-Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q03135
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 20472 Da
Additional Information
Purification Antisera to Caveolin 1 were raised by repeated immunisations of goat with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Peptide sequence C-DELSEKQVYDAH from internal region of Caveolin 1.
Shelf Life 18 months from date of despatch.
Gene ID 857
Other Names Caveolin-1, CAV1, CAV
Target/Specificity Goat anti-Human Caveolin 1 antibody recognizes human caveolin-1, a 178 amino acid, ~21kDa membrane associated protein. Caveolin 1 is a scaffolding protein and the main component of the caveolae plasma membranes found in most cell types (Anderson 1998). Two isoforms of caveolin are generated by alternative initiation, they differ in their N-terminal region with caveolin 1β lacking amino acids 1-31 present in caveolin 1α (Vainonenet al.2004). Goat anti-Human caveolin 1 antibody recognizes epitopes within the region between amino acids 34-41 of caveolin 1α and is therefore expected to recognize both isoforms of caveolin 1Caveolin1 is highly expressed in terminally differentiated or quiescent cells, suggesting a possible role for caveolin 1 as a negative regulator of cell proliferation (Galbiatiet al.2001).Caveolin1 has been implicated in the pathogenesis of oncogenic cell transformation, tumorigenesis, and metastasis (Núñez-Wehingeret al.2014).
Preservative & Stabilisers 0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Caveolin 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Hommel, A. et al. (2010) The ARF-like GTPase ARFRP1 is essential for lipid droplet growth and is involved in the regulation of lipolysis.
Mol Cell Biol. 30: 1231-42.1. Williams, T.M. and Lisanti, M.P. (2005) Caveolin-1 in oncogenic transformation, cancer, and metastasis.
Am. J. Physiol. Cell. Physiol. 288: 494-506.2. Liu, P. et al. (2002) Multiple functions of caveolin-1.
J. Biol. Chem. 277: 41295-41298.

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Cat# ABD10890
(40 western blots)
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