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Anti-Human ERK1 (N-Terminal) Antibody

Goat Anti-Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P27361
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 43136 Da
Additional Information
Purification Antisera to ERK 1 were raised by repeated immunisations of goat with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Peptide with sequence C-GGEPRRTEGVGP from the N-terminal of ERK 1 .
Shelf Life 18 months from date of despatch.
Gene ID 5595
Other Names Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3,, ERT2, Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, p44-MAPK, Microtubule-associated protein 2 kinase, p44-ERK1, MAPK3, ERK1, PRKM3
Target/Specificity ABD10893 detects an epitope within the N-terminal (NT) of extracellular signal-regulated kinase 1 (ERK1). ERK1 is a 45kD protein involved in the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. ERK1 is a member of the MAP kinase (MAPK) family, and is activated by MAP/ERK kinase 1 (MEK1) and MEK2. ERK1 and ERK2, are emerging as important regulators of neuronal responses to both functional and pathologic stimuli.A number of recent studies in models of cerebral ischemia, brain trauma and neurodegenerative diseases implicate a detrimental role for ERK1/2 signalling during oxidative neuronal injury.
Preservative & Stabilisers 0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human ERK1 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Nishimoto, S. and Nishida, E. (2006) MAPK signalling: ERK5 versus ERK1/2.
EMBO Rep. 7: 782-6. 2. Chu, C.T. et al. (2004) Oxidative neuronal injury. The dark side of ERK1/2.
Eur. J. Biochem. 271: 2060–2066.

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Cat# ABD10893
(40 western blots)
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