Register or Login
All
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human Protein Kinase C zeta (N-Terminal) Antibody    

Anti-Human Protein Kinase C zeta (N-Terminal) Antibody

Rabbit Anti-Human Polyclonal Antibody

     
  • IHC - Anti-Human Protein Kinase C zeta (N-Terminal) Antibody  ABD10912
    Staining of formalin fixed, paraffin embedded human cerebellum with Rabbit anti Human protein kinase c zeta
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q05513
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 67660 Da
Additional Information
Purification Antisera to protein kinase C zeta were raised by repeated immunisations of rabbit with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Synthetic peptide: near the N-terminus of human protein kinase C zeta.
Shelf Life 18 months from date of despatch.
Gene ID 5590
Other Names Protein kinase C zeta type, 2.7.11.13, nPKC-zeta, PRKCZ, PKC2
Target/Specificity Rabbit anti-human protein kinase c zeta polyclonal antibody recognizes PKCζ a serine/threonine kinase involved in a variety of cell processes including differentiation and proliferation. PKCζ activation is involved in the mitogen-activated protein kinase cascade, transcriptional factor NFkB activation, ribosomal S6-protein kinase signalling, and cell polarity. Work by Ma.et al. in mice has indicated that inhibition of expression of PHGDH by PKCζ acts at a tumor supressor and that loss of PKCζ allows tumor cells to proliferate under glucose deprived conditions leading to poor prognosis.Rabbit anti-human protein kinase c zeta detects an epitope within the N-terminal (NT) region of PKCζ. PKCζ is a member of the atypical PKC subfamily. PKCζ may also be a potential therapeutic target in asthma, and a putative role in other pulmonary diseases, including chronic obstructive pulmonary disease (COPD).
Preservative & Stabilisers 0.1% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Protein Kinase C zeta (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to
info@abgent.com, and receive a free "I Love Antibodies" mug.

References

1. Hirai, T. and Chida, K. (2003) Protein kinase C zeta (PKC zeta): Activation mechanisms and cellular functions.
J. Biochem. 133: 1-7.

FeedBack
Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at tech@abgent.com.

Cat# ABD10912
Size:
Quantity:
Availability: Inquire
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Terms & Conditions