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Anti-Human USP4 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human USP4 Antibody  ABD10921
    Staining of formalin fixed, paraffin embedded human thymus with Rabbit anti Human ubiquitin specific protease 4
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13107
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 108565 Da
Additional Information
Purification Antisera to USP4 were raised by repeated immunisations of rabbit with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Synthetic peptide: Internal domain of human USP4.
Shelf Life 18 months from date of despatch.
Gene ID 7375
Other Names Ubiquitin carboxyl-terminal hydrolase 4,, Deubiquitinating enzyme 4, Ubiquitin thioesterase 4, Ubiquitin-specific-processing protease 4, Ubiquitous nuclear protein homolog, USP4, UNP, UNPH
Target/Specificity ABD10921 detects an epitope within the internal region of ubiquitin specific protease 4 (USP4), a 105kD protein also known as ubiquitous nuclear protein (UNP). USP4 binds to the retinoblastoma family of tumour suppressor proteins, including pRb, p107 and p130. USP4 shuttles between the nucleus and cytoplasm and is thought to be an oncogene, with elevated expression in small cells tumours and adenocarcinomas of the lung.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human USP4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Blanchette, P. et al. (2001) Association of UNP, a ubiquitin-specific protease, with the pocket proteins pRb, p107 and p130.
Oncogene. 20: 5533-5537.2. Soboleva, T.A. et al. (2005) Nuclear-Cytoplasmic shuttling of the oncogenic mouse UNP/USP4 deubiquitylating enzyme.
J. Bio. Chem. 280: 745-752.3. DeSalle, L.M. et al. (2001) The de-ubiquitinating enzyme Unp interacts with the retinoblastoma protein.
Oncogene. 20: 5538-5542.

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Cat# ABD10921
(40 western blots)
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