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Anti-Human DKK1 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human DKK1 Antibody  ABD10926
    Staining of formalin fixed, paraffin embedded human endometrium with Rabbit anti Human DKK1
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O94907
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 28672 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography
Immunogen Synthetic human DKK1 - KLH conjugated.
Shelf Life 18 months from date of despatch.
Gene ID 22943
Other Names Dickkopf-related protein 1, Dickkopf-1, Dkk-1, hDkk-1, SK, DKK1
Target/Specificity ABD10926 recognises human Dickkopf (Xenopus laevis) homolog 1 (DKK1), a 35kDa to 50kDa member of the dickkopf family. It is expressed in the placenta, prostate and to a lesser extent, in the colon and spleen. DKK1 is secreted when expressed in 293T cells.DKK1 inhibits Wnt signalling in embryonic development, most likely acting upstream of frizzled. It is also thought to contribute to neoplastic processes, inhibit osteoblast differentiation and is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
Preservative & Stabilisers 0.1% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human DKK1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Krupnik, V. et al. (1999) Functional and structural diversity of the human Dickkopf gene family.
Gene. 238:301-13. 2. Fedi, P. et al (1999) Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling.
J. Biol. Chem. 274:19465-19472. 3. Niehrs C. (2006) Function and biological roles of the Dickkopf family of Wnt modulators.
Oncogene. 25:7469-81.

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Cat# ABD10926
(40 western blots)
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