|Calculated MW||41578 Da|
|Purification||Antisera to human TIM-4 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||15 amino acid peptide sequence near the carboxy terminus of human TIM-4.|
|Shelf Life||18 months from date of despatch.|
|Other Names||T-cell immunoglobulin and mucin domain-containing protein 4, TIMD-4, T-cell immunoglobulin mucin receptor 4, TIM-4, T-cell membrane protein 4, TIMD4, TIM4|
|Target/Specificity||ABD10943 detects an epitope within the C-terminal (CT) region of T-cell immunoglobulin mucin-4 (TIM-4), also known as SMUCKLER. TIM-4 is a 42kD type I membrane protein which is preferentially expressed on macrophages and dendritic cells. TIM-4 is the ligand of TIM-1, and binding leads to T-cell proliferation and cytokine production. Polymorphisms in the TIM-4 gene may be associated with a predisposition to asthma.|
|Preservative & Stabilisers||0.02% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-TIM-4 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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