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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Human Stem Cell Factor Antibody    

Anti-Human Stem Cell Factor Antibody

Goat Anti-Human Polyclonal Antibody

     
  • IHC - Anti-Human Stem Cell Factor Antibody  ABD10953
    Formalin fixed, paraffin embedded human pancreatic adenocarcinoma stained with Rabbit anti Human SCF following enzyme mediated antigen retrieval using proteinase K
  • IHC-P - Anti-Human Stem Cell Factor Antibody  ABD10953
    Formalin fixed, paraffin embedded human pancreatic adenocarcinoma stained with Rabbit anti Human SCF following enzyme mediated antigen retrieval using proteinase K
  • IHC-P - Anti-Human Stem Cell Factor Antibody  ABD10953
    Formalin fixed, paraffin embedded human pancreatic adenocarcinoma stained with Rabbit anti Human SCF following enzyme mediated antigen retrieval using proteinase K
  • IHC-P - Anti-Human Stem Cell Factor Antibody  ABD10953
    Formalin fixed, paraffin embedded human pancreatic adenocarcinoma stained with Rabbit anti Human SCF following heat mediated antigen retrieval using EDTA buffer (pH9.0)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E, Func
Primary Accession P21583
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 30899 Da
Additional Information
Purification Antisera to human stem cell factor were raised by repeated immunisations of goats with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Recombinant human stem cell factor.
Shelf Life 12 months from date of reconstitution.
Gene ID 4254
Other Names Kit ligand, Mast cell growth factor, MGF, Stem cell factor, SCF, c-Kit ligand, Soluble KIT ligand, sKITLG, KITLG, MGF, SCF
Target/Specificity Goat anti-Human Stem Cell Factor antibody recognizes human stem cell factor (SCF), a type I transmembrane protein and haematopoietic growth factor, which acts in synergy with other growth factors and signals through the c-Kit receptor.Interaction between SCF and the receptor tyrosine kinase c-Kit is an essential step for the proliferation, survival and differentiation of haematopoietic progenitor cells, mast cells, myelanocytes and germ cells, and plays an important role in follicular development. The association between SCF and c-Kit is also involved with the progression and invasiveness of tumours, and deficiencies of either SCF or c-Kit result in mast cell deficiency and macrocytic anaemia.
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Human Stem Cell Factor Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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References

1. O’ Laughlin-Bunner, B. et al. (2001) Lyn is required for normal stem cell-factor induced proliferation and chemotaxis of primary hematopoietic cells.
BLOOD. 98: 343-350.2. Ronnstrand, L. (2004) Signal transduction via the stem cell factor receptor/c-Kit.
Mol. Life Sci. 61: 2535-2548.

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Cat# ABD10953
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