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>   home   >   Products   >   Primary Antibodies   >   Anti-Rat Synapsin I (pSer549) Antibody    

Anti-Rat Synapsin I (pSer549) Antibody

Rabbit Anti-Rat Polyclonal Antibody

  • WB - Anti-Rat Synapsin I (pSer549) Antibody  ABD10960
    Western blot of rat brain lysate showing phosphospecific immunolabeling of the ~78 kDa synapsin 1 protein phosphorylated at Ser549
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09951
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 73988 Da
Additional Information
Purification Antisera to synapsin I (pSer 549) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Phosphopeptide corresponding to amino acid sequence surrounding the phosphorylated serine 549 of synapsin I.
Shelf Life 12 months from date of reconstitution.
Gene ID 24949
Other Names Synapsin-1, Synapsin I, Syn1
Target/Specificity ABD10960 recognises synapsin I, phosphorylated at serine residue 549. It is a 78 kDa member of the synapsin family, expressed in the central and peripheral nervous system. Synapsins coat synaptic vesicles, binding them to the cytoskeleton and are thought to regulate their availability for release. Synapsins are important in brain plasticity, axonogenesis and synaptogenesis. Mutations in the synapsin I gene may be associated with disorders such as X-linked recessive epilepsy associated with variable learning disabilities and behavior disorders.Phosphorylation of serine residue 549 by MAP kinase or cyclin-dependent kinases 1 or 5 is an important part in modulating synaptic vesicle trafficking.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3); 0.01% Bovine Serum Albumin; 50% Glycerol
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Rat Synapsin I (pSer549) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Baldelli, P. et al. (2005) Synapsins and neuroexocytosis: recent views from functional studies on synapsin null mutant mice.
Arch. Ital. Biol. 143:113-26. 2. Garcia, C. et al. (2004) Identification of a mutation in synapsin I, a synaptic vesicle protein, in a family with epilepsy.
J. Med. Genet. 41:183-187.

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Cat# ABD10960
(40 western blots)
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