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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   Anti-Cyclin E Antibody (Serum)   

Anti-Cyclin E Antibody (Serum)

Rabbit Anti-Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P24864
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 47077 Da
Additional Information
Other Species M,Rat
Purification Antisera to cyclin E were raised by repeated immunisations of rabbits with highly purified antigen.
Immunogen Full length synthetic polypeptide corresponding to the human gene sequence of cyclin E.
Shelf Life 18 months from date of despatch.
Gene ID 898
Other Names G1/S-specific cyclin-E1, CCNE1, CCNE
Target/Specificity ABD10963 detects cyclin E, a nuclear protein which is the regulatory subunit of cyclin dependent kinase 2 (Cdk2), and controls S phase entry in cells. Cyclin E follows a cyclic pattern of expression during the cell cycle, with highest expression at the G1-S boundary. Although cyclin E has an important physiological role in normal cell division, recent reports suggest this function is redundant, and its key functions occur as cells exit quiescence, and in endoreduplication. Cyclin E is tightly regulated during normal cell cycles, but is often deregulated in carcinomas, lymphoma, and leukaemia.
Preservative & Stabilisers 0.01% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Cyclin E Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Hwang, H.C. and Clurman, B.E. (2005) Cyclin E in normal and neoplastic cell cycles.
Oncogene. 24: 2776-2786.2. Zhang H. (2007) Life without kinase: cyclin E promotes DNA replication licensing and beyond.
Mol. Cell. 25: 175-176.

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Cat# ABD10963
(40 western blots)
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