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Anti-CRMP2 (C-Terminal) Antibody (Serum)

Goat Anti-Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16555
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 62294 Da
Additional Information
Purification Antisera to CRMP2 (C-terminal) were raised by repeated immunisations of goats with highly purified antigen.
Immunogen Synthetic peptide corresponding amino acid sequence 543-557 of human CRMP2.
Shelf Life 18 months from date of despatch.
Gene ID 1808
Other Names Dihydropyrimidinase-related protein 2, DRP-2, Collapsin response mediator protein 2, CRMP-2, N2A3, Unc-33-like phosphoprotein 2, ULIP-2, DPYSL2, CRMP2, ULIP2
Target/Specificity ABD10970 recognises collapsin response mediator protein 2 (CRMP2), a ubiquitously expressed, 62 kDa member of the dehydropyrimidinase family. It is involved in axon formation and outgrowth by transporting to axons, the actin cytoskeleton regulating; Rac1-associated protein 1 (Sra-1)/WASP family verprolin-homologous protein 1 (WAVE1) complex. CRMP2 also regulates axon formation and branching by binding tubulin heterodimers thereby enhancing microtubule polymerisation. Through its interaction with ROKalpha, CRMP2 is also thought to play a role in RhoA-dependent signalling. CRMP2 is associated with mesial temporal lobe epilepsy and schizophrenia.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-CRMP2 (C-Terminal) Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Kawano, Y. et al. (2005) CRMP-2 is involved in kinesin-1-dependent transport of the Sra-1/WAVE1 complex and axon formation.
Mol. Cell. Biol. 25:9920-9935.

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Cat# ABD10970
(40 western blots)
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