|Application ||WB, IHC-P, E|
|Calculated MW||40982 Da|
|Purification||Antisera to human Wnt-1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Recombinant human Wnt-1.|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Proto-oncogene Wnt-1, Proto-oncogene Int-1 homolog, WNT1, INT1|
|Target/Specificity||Rabbit anti-Human WNT-1 antibody specifically recognizes Wnt-1, formerly known as int-1, a 343 amino acid non-glycosylated secreted protein associated with the extracellular matrix, involved in normal embryonic development and particularly linked with breast cancer.Wnt-1, which signals through binding to the Frizzled family of transmembrane receptors, was originally identified as a proto-oncogene implicated in carcinomas induced by the mouse mammary tumour virus (MMTV). Wnt-1 belongs to a family of Wnt genes involved in the dorso-ventricular development of the mesoderm during embryogenesis, with a restricted temporal and spatial pattern of expression.|
|Preservative & Stabilisers||Preservative Free|
|Storage||Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.|
|Precautions||Anti-Human WNT-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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