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>   home   >   Products   >   Primary Antibodies   >   Anti-Rat GABA B Receptor 1 (pSer923) Antibody    

Anti-Rat GABA B Receptor 1 (pSer923) Antibody

Rabbit Anti-Rat Polyclonal Antibody

  • WB - Anti-Rat GABA B Receptor 1 (pSer923) Antibody  ABD10985
    Western blot of a rat synaptic membrane showing phosphospecific immunolabeling of the ~102 kDa GABAB R2 protein phosphorylated at Ser923
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Z0U4
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 111534 Da
Additional Information
Purification Antisera to GABAB receptor 1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Synthetic phosphopeptide corresponding to an amino acid sequence within GABAB receptor 1, which includes phosphorylated Ser923.
Shelf Life 12 months from date of reconstitution.
Gene ID 81657
Other Names Gamma-aminobutyric acid type B receptor subunit 1, GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1, Gabbr1
Target/Specificity ABD10985 specifically recognises the 102kDa transmembrane gamma-aminobutyric acid B (GABAB) receptor 1 (GABR1), when phosphorylated at Ser923. GABAB receptors are heterodimeric G-protein coupled receptors which are important mediators of slow neuronal inhibition in the mammalian central nervous system. The functional expression of GABAB receptors on plasma membranes is dependent upon the co-expression of GABR1 and GABR2 (gamma-aminobutyric acid B (GABAB) receptor 2). Phosphorylation of GABR1 at the Ser923 site may be an important factor in the regulation of GABAB receptor function. Abnormalities in the expression or function of GABAB receptors have become a focus area in studies of temporal lobe epilepsy (TLE).
Preservative & Stabilisers 0.09% Sodium Azide (NaN3); 0.01% Bovine Serum Albumin; 50% Glycerol
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Rat GABA B Receptor 1 (pSer923) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Bowery, N.G. et al. (2002) International Union of Pharmacology XXXIII. Mammalian gamma-aminobutyric acidB receptors: structure and function.
Pharmacol. Rev. 54: 247-264.

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Cat# ABD10985
(40 western blots)
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