|Calculated MW||88279 Da|
|Purification||Antisera to human CD26 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic peptide: N-terminal domain of human CD26, conjugated to keyhole limpet hemocyanin (KLH).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Dipeptidyl peptidase 4, 220.127.116.11, ADABP, Adenosine deaminase complexing protein 2, ADCP-2, Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26, TP103, CD26, Dipeptidyl peptidase 4 membrane form, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV soluble form, DPP4, ADCP2, CD26|
|Target/Specificity||Rabbit anti-Human CD26 antibody detects an epitope within the N-terminal region of human CD26, a ~110 kDa protein also known as dipeptidyl peptidase 4 or DPP4. CD26 is a serine protease which is specific for N-terminal proline residues at the penultimate position of a peptide chain, leading to dipeptide release.CD26 is a multifunctional protein that exists as a membrane bound form and a soluble form. CD26 has three major functions including adenosine deaminase (ADA) binding, peptidase activity and extracellular matrix binding, all of which can influence T-cell proliferation and chemotaxis. It has also been shown to be involved in apoptosis.Abnormal CD26 expression is found in autoimmune diseases, HIV-related diseases and cancer.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD26 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Boonacker, E. & Van Noorden, C.J. (2003) The multifunctional or moonlighting protein CD26/DPPIV.Eur J Cell Biol. 82 (2): 53-73.
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