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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human Glycogen Phosphorylase BB Antibody    

Anti-Human Glycogen Phosphorylase BB Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human Glycogen Phosphorylase BB Antibody  ABD10994
    Staining of formalin fixed, paraffin embedded human brain with Rabbit anti Human glycogen phosphorylase BB
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P11216
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 96696 Da
Additional Information
Purification Antisera to human brain glycogen phosphorylase were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Synthetic peptide: internal domain of human brain glycogen phosphorylase, conjugated to Keyhole Limpet Hemocyanin.
Shelf Life 18 months from date of despatch.
Gene ID 5834
Other Names Glycogen phosphorylase, brain form,, PYGB
Target/Specificity Rabbit anti-Human glycogen phosphorylase BB antibody detects brain glycogen phosphorylase, a regulatory enzyme which catalyses the rate-determining step in glycogen degradation. Mammalian glycogen phosphorylase is found as three major isozymes including muscle (GPMM), liver (GPLL), and brain (GPBB), which can be distinguished by their structural and functional properties as well as by the tissues in which they are expressed. GPBB is thought to function in the release of emergency glucose during stress, and in embryogenesis where it is the predominant isozyme. GPBB is also expressed in the early stages of gastric and colorectal cancers.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Glycogen Phosphorylase BB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Holmes, A.P. et al. (2014) Glycogen metabolism protects against metabolic insult to preserve carotid body function during glucose deprivation.
J Physiol. 592 (Pt 20): 4493-506.1. Tashima, S. et al. (2000) Expression of brain-type glycogen phosphorylase is a potentially novel early biomarker in the carcinogenesis of human colorectal carcinomas.
Am J Gastroenterol. 95 (1): 255-63.

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Cat# ABD10994
(40 western blots)
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