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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human CD136 Antibody    

Anti-Human CD136 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human CD136 Antibody  ABD10995
    Staining of formalin fixed, paraffin embedded human colon surface epithelium with Rabbut anti Human CD136
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q04912
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 152271 Da
Additional Information
Purification Antisera to human CD136 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Synthetic peptide: internal domain of human CD136, conjugated to keyhole limpet hemocyanin.
Shelf Life 18 months from date of despatch.
Gene ID 4486
Other Names Macrophage-stimulating protein receptor, MSP receptor,, CDw136, Protein-tyrosine kinase 8, p185-Ron, CD136, Macrophage-stimulating protein receptor alpha chain, Macrophage-stimulating protein receptor beta chain, MST1R, PTK8, RON
Target/Specificity Rabbit anti-Human CD136 antibody detects CD136, a receptor tyrosine kinase also known as Macrophage stimulating 1 receptor (MST1R) and RON (Recepteur d’origine nantais). CD136 is a member of the MET proto-oncogene family, and is the receptor for macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival. CD136 is a disulfide-linked ~180 kDa heterodimer composed of a 40 kDa alpha chain and a 150 kDa beta chain, and is mainly expressed in cells of epithelial origin. In immune cells CD136 expression is restricted to certain types of tissue macrophages, and its activation is critical in modulating macrophage activities and preventing an excessive inflammatory response. CD136 is also required for embryonic development. CD136 expression is significantly altered in several primary human cancers including those of the breast and colon.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD136 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Wang, M.H. et al. (2002) Macrophage-stimulating protein and RON receptor tyrosine kinase: potential regulators of macrophage inflammatory activities.
Scand J Immunol. 56 (6): 545-53.

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Cat# ABD10995
(40 western blots)
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