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Anti-Human FAP alpha Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human FAP alpha Antibody  ABD10996
    Staining of formalin fixed, paraffin embedded human uterus with Rabbit anti Human FAB alpha
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q12884
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 87713 Da
Additional Information
Purification Antisera to FAP alpha were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Synthetic peptide: extracellular domain of human FAP alpha, conjugated to keyhole limpet hemocyanin.
Shelf Life 18 months from date of despatch.
Gene ID 2191
Other Names Prolyl endopeptidase FAP,, 170 kDa melanoma membrane-bound gelatinase, Dipeptidyl peptidase FAP,, Fibroblast activation protein alpha, FAPalpha, Serine integral membrane protease, SIMP, Surface-expressed protease, Seprase, Antiplasmin-cleaving enzyme FAP, soluble form, APCE,, 3.4.21.-,, FAP (HGNC:3590)
Target/Specificity ABD10996 detects fibroblast activation protein alpha (FAP alpha), a type II membrane protein belonging to the serine protease family. FAP alpha is upregulated on activated fibroblasts in response to wounding, and may also be involved in epithelial-mesenchymal interactions during development and tissue repair.Active FAP alpha is a 170kD homodimeric protein which can also exist as a soluble form. FAP alpha can also form heterodimeric complexes with CD26 (DPP4), and these proteins may function co-ordinately to modulate the growth, differentiation, adhesion and metastasis of tumour cells.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human FAP alpha Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Kelly, T. (2005) Fibroblast activation protein-alpha and dipeptidyl peptidase IV (CD26): cell-surface proteases that activate cell signaling and are potential targets for cancer therapy.
Drug Resist. Updat. 8: 51-58.

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Cat# ABD10996
(40 western blots)
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