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Anti-Human CD140b Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human CD140b Antibody  ABD10997
    Staining of formalin fixed, paraffin embedded human renal cortex with Rabbit anti Human CD140b
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09619
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 123968 Da
Additional Information
Purification Antisera to human PDGF receptor beta were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Synthetic peptide corresponding to the extracellular domain of human PDGF receptor beta, conjugated to Keyhole Limpet Hemocyanin.
Shelf Life 18 months from date of despatch.
Gene ID 5159
Other Names Platelet-derived growth factor receptor beta, PDGF-R-beta, PDGFR-beta,, Beta platelet-derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, Platelet-derived growth factor receptor 1, PDGFR-1, CD140b, PDGFRB, PDGFR, PDGFR1
Target/Specificity Rabbit anti-Human CD140b antibody recognizes platelet derived growth factor receptor beta (PDGFRβ), a cell surface tyrosine kinase receptor for platelet-derived growth factor BB. Upon ligand binding PDGFRβ forms homodimers, or heterodimers with PDGFRα, resulting in autophosphorylation. Activated PDGFRs control cell proliferation, migration and survival in mesenchymal cells. CD140b is expressed by non-reticular stromal cells in the bone marrow (Rasiniet al.2013)CD140b has been shown to be important in the recruitment of fibroblasts and pericytes in wound healing.
Preservative & Stabilisers 0.1% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD140b Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Rasini, V. et al. (2013) Mesenchymal stromal/stem cells markers in the human bone marrow.
Cytotherapy. pii: S1465-3249(12)00038-2.

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Cat# ABD10997
(40 western blots)
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