|Calculated MW||127501 Da|
|Purification||Antisera to human TRPA1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||Synthetic peptide: internal domain of human TRPA1, conjugated to Keyhole Limpet Hemocyanin (KLH).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Transient receptor potential cation channel subfamily A member 1, Ankyrin-like with transmembrane domains protein 1, Transformation-sensitive protein p120, TRPA1, ANKTM1|
|Target/Specificity||ABD11000 detects Transient receptor potential A1 (TRPA1), an excitatory cation channel that is highly expressed in nociceptive neurons and plays an important role in inflammatory pain. TRPA1 mediates the response to the proalgesic bradykinin as well as to pungent irritants found in mustards, garlic, and cinnamon.TRPA1 may also be involved in hearing (as the mammalian hair cell mechanotransducer) and in the detection of cold stimuli.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human TRPA1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Story, G.M. and Gereau, R.W. 4th. (2006) Numbing the senses: role of TRPA1 in mechanical and cold sensation. Neuron. 50: 177-180.
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