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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Human Myosin Regulatory Light Chain Antibody    

Anti-Human Myosin Regulatory Light Chain Antibody

Rabbit Anti-Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P24844
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 19827 Da
Additional Information
Purification Antisera to human myosin regulatory light chain were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Immunogen Synthetic peptide corresponding to amino acids 12-27 of human myosin regulatory light chain.
Shelf Life 18 months from date of despatch.
Gene ID 10398
Other Names Myosin regulatory light polypeptide 9, 20 kDa myosin light chain, LC20, MLC-2C, Myosin RLC, Myosin regulatory light chain 2, smooth muscle isoform, Myosin regulatory light chain 9, Myosin regulatory light chain MRLC1, MYL9, MLC2, MRLC1, MYRL2
Target/Specificity ABD11002 detects human myosin regulatory light chain (MRLC), also known as MYL9 and LC20. Myosin is a hexamer composed of two high molecular weight heavy chains and four light chain subunits, which include two alkali light chains and two MRLCs. MRLC functions to stabilize the myosin heavy chain, and may also modulate the availability of cross bridges to bind to actin. Phosphorylation of the MRLC by myosin light chain kinase (MLCK) is necessary for smooth muscle contraction via activating myosin ATPase.This antibody does not detect the sarcomeric/cardiac myosin regulatory light chain isoform.
Preservative & Stabilisers 0.01% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Myosin Regulatory Light Chain Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Nobe, H. et al. (2003) Rho kinase mediates serum-induced contraction in fibroblast fibers independent of myosin LC20 phosphorylation.
Am. J. Physiol. Cell. Physiol. 284: C599-606.

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Cat# ABD11002
(40 western blots)
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