|Calculated MW||173501 Da|
|Purification||Antisera to BAI1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||Synthetic peptide: N-terminal domain of human BAI1, conjugated to Keyhole Limpet Hemocyanin (KLH).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Brain-specific angiogenesis inhibitor 1, BAI1|
|Target/Specificity||ABD11010 detects brain-specific angiogenesis inhibitor (BAI1), a postulated member of the secretin receptor family, which functions as an inhibitor of angiogenesis in the brain. BAI1 is also thought to function in cell adhesion and signal transduction.Reduced expression of BAI1 is observed in some glioblastomas leading to neovascularisation, suggesting that BAI1 may be an excellent gene therapy candidate for the treatment of brain tumours. BAI1 is also thought to be transcriptionally regulated by p53.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human BAI1 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Kang, X. et al. (2006) Antiangiogenic activity of BAI1 in vivo: implications for gene therapy of human glioblastomas.Cancer Gene Ther. 13: 385-392.
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