|Calculated MW||51306 Da|
|Purification||Antisera to human ERR gamma were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||Synthetic peptide: N-terminal domain of human ERR gamma, conjugated to Keyhole Limpet Hemocyanin (KLH).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Estrogen-related receptor gamma, ERR gamma-2, Estrogen receptor-related protein 3, Nuclear receptor subfamily 3 group B member 3, ESRRG, ERR3, ERRG2, KIAA0832, NR3B3|
|Target/Specificity||ABD11011 detects estrogen-related receptor gamma (ERR gamma), a member of the nuclear hormone receptor superfamily. The fasting-induced coactivator protein PGC-1a has been shown to activate the ERR gamma, and together these proteins have a major role in the regulation of ERR alpha gene expression and energy homeostasis. ERR gamma and alpha are co-expressed in high energy demanding tissues such as skeletal muscle heart and kidney, and have been suggested to function in their differentiation. ERR gamma has also been shown to be over-expressed in breast tumours, and has been suggested to be a potential biomarker for favourable clinical course and hormonal sensitivity.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human ERR gamma (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Zhang, Z. and Teng, C.T. (2007) Interplay between estrogen-related receptor alpha (ERRalpha) and gamma (ERRgamma) on the regulation of ERRalpha gene expression.Mol. Cell. Endocrinol. 264: 128-141.
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