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Anti-Human OGR1 (N-Terminal) Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human OGR1 (N-Terminal) Antibody  ABD11013
    Staining of formalin fixed, paraffin embedded human testis with Rabbit anti Human OGR1
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15743
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 41077 Da
Additional Information
Purification Antisera to human OGR1 (NT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Synthetic peptide: N-terminal domain of human OGR1, conjugated to Keyhole Limpet Hemocyanin (KLH).
Shelf Life 18 months from date of despatch.
Gene ID 8111
Other Names Ovarian cancer G-protein coupled receptor 1, OGR-1, G-protein coupled receptor 68, GPR12A, Sphingosylphosphorylcholine receptor, GPR68, OGR1
Target/Specificity ABD11013 detects ovarian cancer G protein-coupled receptor 1 (OGR1), a seven pass transmembrane protein initially cloned from an ovarian cancer cell line. OGR1 has a wide expression, and selectively binds both protons and bioactive lipids. OGR1 functions as a proton-sensing G protein-coupled receptor stimulating inositol phosphate production and Ca2+ mobilisation. It is also a receptor for sphingophosphorylcholine and related lysolipids, which antagonise the proton-induced actions mediated by OGR1. OGR1 is also expressed early during osteoclastogenesis and plays a role in osteoclast differentiation.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human OGR1 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Mogi, C. et al. (2005) Sphingosylphosphorylcholine antagonizes proton-sensing ovarian cancer G-protein-coupled receptor 1 (OGR1)-mediated inositol phosphate production and cAMP accumulation.
J. Pharmacol. Sci. 99: 160-167.

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Cat# ABD11013
(40 western blots)
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