|Calculated MW||45085 Da|
|Purification||Antisera to human TRHR (CT) were raised by repeated immunisations of rabbit with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||Synthetic peptide: C-terminal domain of human Thyrotropin-releasing hormone receptor, conjugated to Keyhole Limpet Hemocyanin (KLH).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Thyrotropin-releasing hormone receptor, TRH-R, Thyroliberin receptor, TRHR|
|Target/Specificity||ABD11015 detects thyrotropin-releasing hormone receptor (TRHR), a G protein-coupled receptor which binds the tripeptide thyrotropin releasing hormone (TRH). TRH is a hypothalamic neuropeptide that controls the synthesis and release of prolactin and thyroid stimulating hormone (TSH) from the anterior pituitary gland.TRHR is widely distributed in the central nervous system, but also plays an important role in central cardiovascular regulation; as hypertensive patients have a blunted TSH response suggesting a defect in TSH release mediated by TRHR activation.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human TRHR (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. García, S.I. et al. (2001) Thyrotropin-releasing hormone receptor (TRHR) gene is associated with essential hypertension.Hypertension. 38: 683-687
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