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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Mouse Glutathione Peroxidase 4 (Ct) Antibody    

Anti-Mouse Glutathione Peroxidase 4 (Ct) Antibody

Rabbit Anti-Mouse Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O70325
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 22229 Da
Additional Information
Purification Antisera to mouse Glutathione peroxidase 4 (CT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Synthetic peptide corresponding to amino acids near the carboxyl terminus of mouse glutathione peroxidase 4.
Shelf Life 18 months from date of despatch.
Gene ID 625249
Other Names Phospholipid hydroperoxide glutathione peroxidase, mitochondrial, PHGPx, 1.11.1.12, Glutathione peroxidase 4, GPx-4, GSHPx-4, Gpx4
Target/Specificity ABD11016 detects a specific epitope within the carboxy-terminal of mouse glutathione peroxidise 4 (GPx4) also known as phospholipid hydroperoxidase (PHGPx). GPx4 is a 20-22kDa selenoprotein that has an important role in preventing lipid peroxidation, and is thought to protect biomembranes against oxidative stress. GPx4 is expressed in high levels in testes, suggesting a role in male fertility. It has also been identified as an enzymatically inactive structural protein of the mitochondrial capsule of sperm. GPx4 has also been proposed as a modulator of various eicosanoids, which serve as inflammatory lipid signalling molecules.
Preservative & Stabilisers 0.01% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse Glutathione Peroxidase 4 (Ct) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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References

1. Nakagawa Y. (2004) Role of mitochondrial phospholipid hydroperoxide glutathione peroxidase (PHGPx) as an antiapoptotic factor.
Biol. Pharm. Bull. 27: 956-960.

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Cat# ABD11016
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