|Calculated MW||107197 Da|
|Purification||Antisera to human PIB5PA were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic Peptide corresponding to the N-Terminal domain of Human PIPB5PA, conjugated to keyhole limpet hemocyanin (KLH).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Phosphatidylinositol 4, 5-bisphosphate 5-phosphatase A, 188.8.131.52, Inositol polyphosphate 5-phosphatase J, INPP5J, PIB5PA, PIPP|
|Target/Specificity||ABD11017 detects phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A (PIB5PA) also known as PIPP (proline-rich inositol polyphosphate 5-phosphatase) . PIB5PA functions as a negative regulator of PI3-kinase signalling events that promote neurite elongation and survival, and is thought to regulate the level of inositol and phosphatidylinositol polyphosphates at membrane ruffles. PIB5PA is constitutively associated with the plasma membrane, and is expressed in a number of tissues including the brain, heart, kidney, stomach, small intestine and lung.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human PIB5PA (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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