|Calculated MW||55010 Da|
|Purification||Antisera to human CD98LC were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic Peptide corresponding to an internal domain of the Human CD98LC.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Large neutral amino acids transporter small subunit 1, 4F2 light chain, 4F2 LC, 4F2LC, CD98 light chain, Integral membrane protein E16, L-type amino acid transporter 1, hLAT1, Solute carrier family 7 member 5, y+ system cationic amino acid transporter, SLC7A5, CD98LC, LAT1, MPE16|
|Target/Specificity||Rabbit anti-human CD98 light chain antibody recognises an internal domain of the Human CD98 light chain (CD98LC), also known as the 4F2 light chain, or LAT-1. CD98LC is a 55kDa multi-pass membrane protein which forms a heterodimer with the CD98 heavy chain to allow transport of large branched chain, neutral amino acids into the cell. This transport system leads to the uptake of seven amino acids, including isoleucine, phenylalanine, and methionine. The expression levels of CD98LC are upregulated in a wide spectrum of primary human cancers. Changes in amino acid transporter expression are thought to be an early change in oncogenesis, as they impart growth and survival advantages.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD98 Light Chain Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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